Return to fertility after extended chemical castration with a GnRH antagonist
نویسندگان
چکیده
منابع مشابه
Switching of GnRH Agent from Agonist to Antagonist in Patients with Castration-Resistant Prostate Cancer
Objectives: To evaluate the efficacy of alteration from gonadotropin-releasing hormone (GnRH) agonist to antagonist in patients with castration-resistant prostate cancer (CRPC). Methods: Fourteen patients with CRPC were switched from GnRH agonist to GnRH antagonist. CRPC was defined as 3 consecutive rises of PSA values under androgen deprivation therapy despite a testosterone level at the castr...
متن کاملAssessment of fertility protection and ovarian reserve with GnRH antagonist in rats undergoing chemotherapy with cyclophosphamide
BACKGROUND Reproductive function following chemotherapy is of increasing importance given that survival rates are improving. We assessed whether a gonadotropin-releasing hormone antagonist (GnRHant; cetrorelix) could promote ovarian protection against damage due to chemotherapy. METHODS Forty-two female Wistar rats were used in this study. Animals were divided into four groups: group I (n=9) ...
متن کاملA Flexible Multidose GnRH Antagonist versus a Microdose Flare-Up GnRH Agonist Combined with a Flexible Multidose GnRH Antagonist Protocol in Poor Responders to IVF
OBJECTIVE To compare the effectiveness of a flexible multidose gonadotropin-releasing hormone (GnRH) antagonist against the effectiveness of a microdose flare-up GnRH agonist combined with a flexible multidose GnRH antagonist protocol in poor responders to in vitro fertilization (IVF). STUDY DESIGN A retrospective study in Akdeniz University, Faculty of Medicine, Department of Obstetrics and ...
متن کاملRandom-start GnRH antagonist for emergency fertility preservation: a self-controlled trial
The aim of this study is to evaluate the feasibility and safety of random-start controlled ovarian hyperstimulation (COH) for emergency fertility preservation, regardless of the phase of the menstrual cycle. A self-controlled pilot clinical trial (NCT01385332) was performed in an acute-care teaching hospital and in two private reproductive centers in Barcelona, Spain. Eleven egg donors particip...
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ژورنال
عنوان ژورنال: BMC Cancer
سال: 2001
ISSN: 1471-2407
DOI: 10.1186/1471-2407-1-18